No More Room in Hell 2 Responders (Characters & Classes) Guide

Responders are the playable characters — and the thing permadeath takes from you. You hold up to three active Responders; creating a new one deals you three random candidates, each with a starting skill tied to their pre-outbreak profession, and a reroll costs 50 credits. Names are randomly generated; there are no fixed "classes" — your profession start plus level-up picks (levels 5–50) define the build.

Every profession and its starting skill

The full job → skill table, with our take on which starts are worth keeping:

Pre-outbreak jobStarting skill(s)Worth keeping?
Football MVPMarathon Runner / Adrenaline RushBest all-round start — run-stamina is the strongest early skill in the game.
Track StarAthlete / DoorbreakerStamina pool for melee mains; Athlete start is a top-3 roll.
Swim CaptainThick SkinFlat max health — never a wasted start.
PrepperScavenger / BuilderScavenger fights calibre scarcity from minute one.
SheriffOverkillThe shotgun-lane start; pairs with Deputy's Tight Shot.
DeputyTight Shot / WickedThe other half of the shotgun package.
Designated MarksmanSteel ChamberHeavy-rifle damage for .308 builds.
DetectiveLocked On / HeadblownPistol/SMG lane; Headblown pushes one-shot breakpoints.
NurseSkilled Medic / Acquired ImmunityThe infection-resist start — squad value.
ParamedicResident Genes / Stayin' AliveThe co-op medic; fast revives save runs.
Spinal SurgeonHitmanOne-handed melee damage — Hand Axe builds.
MMA FighterSturdy BodyFlat damage reduction; tank lane.
Army ReservistHellfire / MohawkRifle lane starts.
Hockey PlayerRush / ForemanTwo-handed melee stamina economy.
CourierCaravan / MuleWeight trades — situational at best.
Deer HunterQuiet Steps (Averaging removed in 1.0)Stealth is fine — and the start improved when 1.0 cut Averaging from the pool.

Other recorded jobs: Bear Hunter (Penetrating Shot), Bird Hunter (Icarus), Coast Guard Veteran (Limbo), Engineer (Longer Battery), Lumberjack (Resilience), Marine Veteran (Winged / Steady Shot), Martial Arts Master (Heavy Shoves), Police Sniper (Eagle Eye), Prop Master (Grenadier), Quartermaster (Vulture / Deprived), Rescue Specialist (Lucky Pathogen / Healing Item Stack), Sous Chef (Butcher), Baseball Rookie (Hard Blow — its other EA skill, Teddy Bear, was removed at 1.0 along with Averaging and Guts).

Which start should you reroll for?

Don't burn credits chasing perfection — but the standout starts are Football MVP (Marathon Runner), Track Star (Athlete), Swim Captain (Thick Skin) and Prepper (Scavenger): the same four skills that top our skills tier list. Weapon-lane starts (Sheriff, Deputy, Designated Marksman, Detective) are great if you commit to that lane on the weapons tier list.

Deleting and customization

You can delete a Responder from the Character tab to free a slot — their loadout purchases die with them, so strip anything you can first. Customization has grown steadily: the 0.5.0 update introduced it, 0.8 Genesis added full control over preset head, skin tone, hair, eye color and voice, and 1.0 expanded the outfit catalog with new cosmetic types (compass and flashlight skins) purchasable with Credits or the new Merits currency.